| Cheeca Lodge & Spa | 81801 Overseas Hwy, Islamorada | $99 - 715 |
| Comfort Inn | 3824 North Roosevelt Blvd., Key West | $70 - 670 |
| Crowne Plaza La Concha Hotel | 430 Duval Street, Key West | $110 - 670 |
| Days Inn Key West | 3852 N Roosevelt, Key West | $70 - 270 |
| Fairfield Inn Key West | 2400 N Roosevelt Blvd., Key West | $76 - 115 |
| Hilton Resort & Marina Hotel | 245 Front Street, Key West | $165 - 499 |
| Holiday Inn Beachside | 3841 North Roosevelt Blvd., Key West | $90 - 449 |
| Holiday Inn Key Largo | 99701 Overseas Highway, Key Largo | $100 - 270 |
| Holiday Inn Resort & Marina | 13201 Overseas Hwy. Mm 54, Marathon | $86 - 420 |
| Howard Johnson Resort Hotel | Bayside At Mm 102 Overseas Hwy, Key Largo | $60 - 260 |
| Hyatt Regency Key West Resort Hotel | 601 Front Street, Key West | $250 - 563 |
| Lime Tree Bay Resort Hotel | 68500 Overseas Hwy., Layton Long Key | $130 - 168 |
| Marriott Bay Beach Resort Hotel | 103800 Overseas Highway, Key Largo | $150 - 158 |
| Marriott Courtyard On The Gulf Hotel | 3420 N Roosevelt Blvd, Key West | $23 - 410 |
| Ocean Key Resort Hotel | Zero Duval Street, Key West | $260 - 407 |
| Quality Inn & Suites | 3850 N Roosevelt Boulevard, Key West | $90 - 460 |
| Radisson Hotel Key West | 3820 Roosevelt Road, Key West | $99 - 499 |
| Ramada Limited Hotel | 99751 Overseas Highway, Key Largo | $100 - 180 |
| Ramada Marathon Oceanview Hotel | 13351 Overseas Highway, Marathon | $86 - 272 |
| The Gardens Hotel | 526 Angela Street, Key West | $205 - 400 |
| Westin Beach Resort Key Largo Hotel | 97000 South Overseas Hwy., Key Largo | $37 - 1158 |
| Wyndham Casa Marina Hotel | 1500 Reynolds Street, Key West | $150 - 464 |
| Wyndham Reach Resort Hotel | 1435 Simonton St., Key West | $150 - 464 |
| Almond Tree Inn | 512 Truman Avenue, Key West | $139 - 350 |
| Banyan Resort Hotel | 323 Whitehead Street, Key West | $165 - 165 |
| Blue Skies Inn | 630 South Street, Key West | $99 - 379 |
| Budget Key West Hotel | 1031 Eaton Street, Key West | $69 - 199 |
| Bw Hibiscus Motel Hotel | 1313 Simonton St, Key West | $89 - 309 |
| Chelsea House Hotel | 707 Truman Avenue, Key West | $125 - 165 |
| Coconut Mallory At Key West Hotel | 1445 S Roosevelt Blvd, Key West | $212 - 250 |
| Duval House Hotel | 815 Duval Street, Key West | $115 - 175 |
| Eighteen Hundred Atlantic Hotel | 1800 Atlantic Bvld, Key West | $245 - 295 |
| El Rancho Motel Hotel | 830 Truman Ave, Key West | $75 - 339 |
| Garden House Hotel | 329 Elizabeth Street, Key West | $120 - 135 |
| Hampton Inn Key West | 2801 N Roosevelt, Key West | $85 - 209 |
| Heron House Hotel | 512 Simonton St, Key West | $149 - 349 |
| Hilton Sunset Key Cottages Hotel | 245 Front Street, Key West | $415 - 1825 |
| Hyatt Beach House Resort Hotel | 5051 Overseas Highway, Key West | $198 - 475 |
| Hyatt Sunset Harbor Resort Hotel | 200 Sunset Lane, Key West | $500 - 500 |
| Hyatt Winward Pointe Hotel | 3675 S Roosevelt Blvd, Key West | $165 - 375 |
| Island City House Hotel | 411 William Street, Key West | $180 - 340 |
| Island Place Hotel | 817 Catherine Street, Key West | $79 - 499 |
| Islander Resort Hotel | Mm 82 1 Oceanfront, Islamorada | $99 - 189 |
| Key Lime Inn | 725 Truman Avenue, Key West | $82 - 369 |
| La Mer And Dewey House Hotel | 506-508 South Street, Key West | $335 - 425 |
| Marquesa Hotel | 600 Fleming St, Key West | $225 - 410 |
| Merlin Guesthouse Hotel | 811 Simonton Street, Key West | $79 - 199 |
| Paradise Inn | 819 Simonton Street, Key West | $210 - 400 |
| Pegasus International Hotel | 501 Southard Street, Key West | $150 - 293 |
| Pier House Resort &carri Spa Hotel | 1 Duval Street, Key West | $224 - 460 |
| Red Rooster Inn | 709 Truman Avenue, Key West | $115 - 170 |
| Santa Maria Of Keywest Hotel | 1401 Simonton Street, Key West | $59 - 199 |
| Southernmost On The Beach Hotel | 508 South St, Key West | $119 - 289 |
| Sunrise Suites Resort Hotel | 3685 Seaside Drive, Key West | $180 - 180 |
| The Southernmost Hotel | 1319 Duval St, Key West | $89 - 219 |
| Travelodge Suites Bayside | 3444 North Roosevelt Blvd, Key West | $98 - 469 |
Popular hotels nearby Duck Keys:
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